warfarin (Coumadin) (vit K antag)
Class:
Anticoagulants: Oral Anticoagulants: Coumarins
Indication:
Prevention and treatment of thromboembolic disorders (e.g., DVT, PE, AFIB with thrombus). Prevention of complications following an MI.
Mode of Action:
Antagonizes vitamin K, preventing formation of several clotting factors.
Cautions:
Not in source
Indication:
GI upset, hepatitis, Life-threatening bleeding.
NC/PT:
Closely monitor PT/INR levels. Therapeutic INR is 2 - 3 (takes 5 - 7 days to get to a therapeutic level). Antidote is vitamin K! Maintain a consistent dietary intake of vitamin K. Bleeding precautions (card 24).