indomethacin (Indocin)
Class:
Analgesics: Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Indication:
Mild to moderate pain, fever, inflammation.
Mode of Action:
Analgesia by ↓ inflammation.
Cautions:
Pregnancy, peptic ulcer disease (PUD), bleeding disorders.
Indication:
GI upset, nephrotoxicity, GI bleeding, ulceration, perforation. ↑ Risk of cardiovascular thrombotic events (e.g., MI, stroke).
NC/PT:
Interactions: Corticosteroids, alcohol (concurrent use ↑ risk of GI bleed).