divalproex (Depakote)

Class:

Mood Stabilizers/Anticonvulsants: Valproates

Indication:

Bipolar disorder, seizures.

Mode of Action:

↑ GABA in CNS to ↓ manic episodes related to bipolar disorder and suppress seizure activity.

Cautions:

Not in source

Indication:

GI upset, thrombocytopenia, Hepatotoxicity, pancreatitis, fetal risk.

NC/PT:

Monitor liver function (AST, ALT, LDH, bilirubin) and CBC levels during therapy. Baseline liver labs needed prior to initiation of therapy.